Actionable Patient Safety Solutions (APSS)

22E Central Line-Associated Bloodstream Infections

A Central Line-Associated Bloodstream Infection (CLABSI) in one patient can result in as much as $56,000 for payers, due to a mortality rate of 14-40% and an average prolonged length of stay of between 7.5 and 25 days (Ranji et al., 2007). Researchers estimate that process change and the use of technology to reduce CLABSI can save up to $2.7 billion per year while significantly improving quality and safety (Scott, 2009). The implementation of a CLABSI bundle has been shown to reduce cases by up to 74% (IHI, 2012). Yet, translating the best practices, like those in the CLABSI bundle, into reliable frontline processes is immensely challenging due to human factors in an ever-changing environment.

Our APSS outline actionable steps healthcare organizations should take to successfully implement and sustain behavior change for high reliability, shared understanding, thorough communication, and meaningful person-centered care across the organization.

Actionable steps include:

  • Executive Summary Checklist
  • Leadership checklist guide to determine whether current evidence-based guidelines are being followed in your organization
  • Performance improvement plan to follow if improvements are necessary
  • Clinical workflow for preoccupation with workflow for areas of improvement
  • How to educate patients and family members about the significance of their role throughout the continuum
  • Guidance on how to measure outcomes

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APSS are revised annually and available free of charge on our website for download.


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